abstract：:Viral gastroenteritis is a major public health problem worldwide, and the number of identified pathogens continuously increases. Investigators have made considerable progress toward understanding both the epidemiology and the mechanisms of virus-cell interactions, host responses, and pathogenesis. A vaccine for the mo...

journal_title：Current opinion in gastroenterology

authors： Shaw RD

更新日期：2000-01-01 00:00:00

abstract：:Colon carcinogenesis is a multistep process that involves deletions, mutations, and changes in expression of genes that regulate growth, differentiation, and apoptosis. Hyperproliferation can initiate dysplastic growth, resulting in accumulation of genetic defects and progression of colon cancer. Although genetic inst...

journal_title：Current opinion in gastroenterology

authors： Singh P,Dai B,Wu H,Owlia A

更新日期：2000-01-01 00:00:00

abstract：:In the past year, numerous important papers were published on chronic pancreatitis, its causes, and its diagnosis; the cause of fibrosis; and pain in pancreatic cancer. More than 750 mutations have been described in the cystic fibrosis transmembrane regulator (CFTR) gene. Some mutations cause relatively mild reduction...

journal_title：Current opinion in gastroenterology

authors： Chari ST,Dimagno EP

更新日期：1999-09-01 00:00:00

abstract：:In spite of expanding knowledge of cellular and molecular mechanisms of intestinal inflammation, the etiology and pathogenesis of inflammatory bowel disease (IBD) remain obscure. The link between the environment and IBD is still circumstantial, but definite progress is occurring in defining genetic susceptibility loci...

journal_title：Current opinion in gastroenterology

authors： Katz JA,Itoh J,Fiocchi C

更新日期：1999-07-01 00:00:00

abstract：:The treatment of patients with unexplained chest pain is difficult and challenging. After a cardiac etiology has been ruled out, a diligent search for an esophageal etiology-gastroesophageal reflux disease, motility abnormalities, or esophageal hypersensitivity-should be undertaken with judicious use of a diagnostic (...

journal_title：Current opinion in gastroenterology

authors： Katz PO

更新日期：1999-07-01 00:00:00

abstract：:Viral hepatitis is still one of the most common causes of acute and chronic liver disease worldwide. Major advances have been made in our knowledge of these diseases, many during the past year. Molecular biology and clinical studies have improved our understanding of the mechanisms of antiviral drugs, as well as viral...

journal_title：Current opinion in gastroenterology

authors： Regev A,Schiff ER

更新日期：1999-05-01 00:00:00

abstract：:Interesting advances occurred recently in nutrient absorption. Kinetics of triacylglycerol appearance in endoplasmic reticulum, Golgi apparatus, and lymph support the hypothesis that endoplasmic reticulum-to-Golgi transport is rate-limiting for lipid absorption. Apolipoprotein B does not appear necessary for initial f...

journal_title：Current opinion in gastroenterology

authors： Nutting DF,Kumar NS,St Hilaire RJ,Mansbach CM 2nd

更新日期：1999-03-01 00:00:00

abstract：:This article provides an overview of advances in understanding the cellular and molecular mechanisms and regulation of intestinal absorption processes of vitamins. The vitamins covered are the water-soluble vitamins folic acid, cobalamin (vitamin B12), biotin, pantothenic acid, and thiamine (vitamin B1) and the lipid-...

journal_title：Current opinion in gastroenterology

authors： Said HM,Kumar C

更新日期：1999-03-01 00:00:00

abstract：:The development of colorectal neoplasms can be characterized by an ordered series of events that are referred to as the dysplasia-carcinoma sequence. These histologic changes occur as a result of genetic alterations in proto-oncogenes and tumor-suppressor genes. This review emphasizes important studies characterizing ...

journal_title：Current opinion in gastroenterology

authors： Shattuck-Brandt RL,DuBois RN

更新日期：1999-01-01 00:00:00

abstract：:Intensive investigation into the interactions of Helicobacter pylori with the human host during the period of this review has led to several important developments in our understanding of H. pylori pathogenesis. There is direct evidence to support a central role for bacterial adhesion to host gastric epithelial Lewis ...

journal_title：Current opinion in gastroenterology

authors： Wilson KT,Fantry GT

更新日期：1999-01-01 00:00:00